Manufacturer: Merial Australia Pty Limited Registered Name Equimec Plus Tape Roundworm, Tapeworm and Bot Treatment for Horses Composition Ivermectin 8 mg/g; praziquantel 100 mg/g. Actions Ivermectin acts by binding to glutamate gated chloride channels which occur in invertebrate nerve and muscle cells. This leads to hyperpolarisation of these cells, resulting in paralysis and death of the parasite. Compounds of this class may also interact with other ligand gated chloride channels such as those gated by the neurotransmitter gamma-aminobutyric acid (GABA). Praziquantel is a synthetic isoquinoline-pyrazine derivative. Indications Treatment and control of roundworms (including arterial larval stages of Strongylus vulgaris and benzimidazole resistant small strongyles), tapeworms, bots and skin lesions (summer sores) caused by Habronema and Draschia sp. and Onchocerca sp. (cutaneous onchocerciasis). At the recommended dose level, Equimec Plus Tape controls the following parasites in horses. Tapeworms: Anoplocephala perfoliata, Anoplocephala magna, Paranoplocephala mammillana (adult and immature, heads and segments); large strongyles: Strongylus vulgaris (adults and arterial larval stages), Strongylus edentatus (adults and tissue stages), Strongylus equinus (adults) and Triodontophorus sp. (adults); small strongyles including benzimidazole resistant strains Cyathostomum sp., Cylicocyclus sp., Cylicostephanus sp., Cylicodontophorus sp., Gyalocephalus sp.; pinworms: Oxyuris equi (adult and immature); ascarids: Parascaris equorum (adult and immature); hairworms: Trichostrongylus axei (adult); large mouthed stomach worms: Habronema muscae (adult); neck threadworms: Onchocerca sp. (microfilariae); bots: Gasterophilus sp. (oral and gastric stages); lungworms: Dictyocaulus arnfieldi (adult and immature); intestinal threadworms: Strongyloides westeri (adult). Control of skin lesions caused by Habronema and Draschia sp. cutaneous larvae (summer sores), and Onchocerca sp. microfilariae (cutaneous onchocerciasis). Precautions Safety directions Harmful if swallowed. Will irritate the eyes and skin. Avoid contact with skin and eyes. Wash hands after use. If product in eyes, wash it out immediately with water. First Aid If poisoning occurs contact a doctor or Poisons Information Centre. Phone Australia 131 126. Disposal Dispose of empty syringe by wrapping with paper and putting in garbage. Ivermectin is extremely toxic to aquatic species. Do not contaminate dams, rivers, streams or other waterways with the product or used container. Withholding Periods Meat 28 days. Dosage and Administration 1 mL /40 kg bodyweight administered orally; this dose rate delivers ivermectin 0.2 mg/kg and praziquantel 2.5 mg/kg. Each weight marking on the syringe plunger delivers 2.5 g paste which is sufficient to treat 100 kg bodyweight. The contents of one syringe will treat a horse at 600 kg bodyweight. May be used in horses of all ages including pregnant mares and breeding stallions.
