Manufactuer: Mavlab Pty Ltd Composition Levamisole hydrochloride 20 mg, praziquantel 4 mg. Actions Anthelmintic. The major mode of action of levamisole is on the cholinergic receptor of the neuromuscular junction, causing paralysis of the parasite. Levamisole has been shown to inhibit fumarate reductase and to affect the rate of incorporation of glucose into glycogen. Praziquantel is a highly specific cestocidal drug that acts by damaging the tegument, inhibiting glucose uptake and stimulating lactate release. Tapeworms are destroyed in situ. Use to treat Threadworm (Capillaria sp.), caecal worm (Heterakis sp.), roundworm (Ascaridia sp.), gape worm (Syngamus sp.), gizzard worm (Acuaria sp.) and tapeworm (Raillietina sp.) in caged birds over 250 g in bodyweight. Contraindications Administration to species or strains of birds known to be sensitive to the effects of levamisole.
Precautions Parrots appear to be less tolerant than pigeons to levamisole. Do not dose in extremely hot, dry weather or treat stressed birds, or birds that are feeding young. Treatment during the breeding season or of racing pigeons is not recommended. Vomiting may occur (see Adverse Reactions). To reduce the likelihood of vomiting, do not handle birds for at least ten minutes after treatment. If worm problems persist consult a veterinarian. Safety directions. Harmful if swallowed. Avoid contact with eyes and skin. Wash hands after use. First aid. If poisoning occurs, contact a doctor or Poisons Information Centre. Phone Australia 131 126. Withholding Periods Do not use in food producing species. Adverse Reactions Side effects include regurgitation (which is not considered to be harmful), incoordination, leg and wing paresis; atropine has been used as an antidote. Deaths of birds up to two days after dosing have been attributed to obstruction from massive roundworm infestation. Dosage and Administration Administer orally directly into the throat at the rate of levamisole hydrochloride 40 mg/kg bodyweight and praziquantel 8 mg/kg bodyweight, as follows. 250 to 500 g bodyweight. 1/2 tablet. 500 to 750 g bodyweight. 1 tablet. 750 g to 1 kg bodyweight. 1 1/2 tablets. Do not feed birds for 24 hours before or three hours after treatment. All birds in the same loft or cage should be treated and the loft or cage cleaned and disinfected three days after treatment.
